Interaction and effects of binary exposure of platinum and palladium in invertebrates inhabiting freshwater metal-contaminated water and sediments - Jobs in Montréal, QC

Job Description

Interaction and effects of binary exposure of platinum and palladium in invertebrates inhabiting freshwater metal-contaminated water and sedimentsRéf ABG-106306 Sujet de Thèse16/06/2022 CifreUniversité du Québec in MontréalLieu de travailMontréal - CanadaIntitulé du sujetInteraction and effects of binary exposure of platinum and palladium in invertebrates inhabiting freshwater metal-contaminated water and sedimentsChamps scientifiques

• Ecologie, environnement

Mots clésplatinum, palladium, Chironomides riparius, Hyalella azteca, environmental proteomic, metallomicsDescription du sujetPhD position in Aquatic EcotoxicologySummaryCurrent ecological risk assessments (ERA) are based on toxicological measurements that are typically made using single metals, are not under real-world metal-mixture scenarios. For that reason, thorough scientific investigation of the behaviour and toxicity of naturally combined trace metals is urgently needed. To address this knowledge gap, research on emerging contaminants such as platinum-group elements (e.g., platinum (Pt) and palladium (Pd)) are currently suitable since their emissions lead to increasing environmental concentrations that raises clear concern over the potential risk of these metals. The objective of this PhD project is to determine the toxicological interactions of binary exposure scenarios of Pt and Pd in two aquatic invertebrates, namely Chironomides riparius and Hyalella azteca. These organisms will be exposed to binary combinations to determine the interaction between them and the resulting toxicity at different levels (molecular, subcellular and organismal).This project applies approaches related to environmental proteomic and metallomics, such as subcellular metal partitioning approach and hyphenated techniques (e.g., SEC-ICP-QQQ; RP-HPLC ICP-QQQ). The candidate will have access to advanced analytical platforms located in both universities. This research will reveal information about the molecular and subcellular mechanisms by which trace metals interact and exert deleterious effects, and will identify potential biomarkers of toxicity or exposure of metal mixtures. All these results will greatly contribute to the development of more reliable and realistic models to predict the potential effects of trace elements in aquatic systems.Start date: September 2022 is preferred but negotiable.Funding: PhD scholarship offer for 4 years. Possibility to apply to other scholarship support (GRIL; EcotoQ; Faculty of Sciences, UQAM)Closing date for applications: 31 July 2022 (preferred). Once all applications have been received, the selection process will begin and will continue until the position is filled.Contact: Maikel Rosabal, Département des sciences biologiques, Université du Québec à MontréalNature du financementCifrePrécisions sur le financement21 000$ CADPrésentation établissement et labo daccueilUniversité du Québec in MontréalDépartement des sciences biologiquesUniversité du Québec à Montréal (UQAM)Site web :http://rosabal-laboratory.com/Intitulé du doctoratDoctorat en sciences biologiquesPays dobtention du doctoratCanadaProfil du candidatRequirements: To meet the eligibility requirements for the PhD in Biology research program offered by UQAM; Background and skills in environmental chemistry, biochemistry, biology, toxicology, analytical chemistry or other related fields; Good skills in laboratory work, Strong interest in scientific research and environmental toxicity, Knowledge of spoken and written French and/or English.Quick Apply

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