Manager, In-House Manufacturing - Jobs in Vancouver, BC

Job Description

Company Profile: Genevant is a technology-focused nucleic acid delivery company with world-class platforms, the industry’s most robust and expansive lipid nanoparticle (LNP) patent estate and decades of experience and expertise in nucleic acid drug delivery and development. We leverage our world-class delivery systems to bring new medicines to patients who need them, in collaboration with leading pharma companies. Our laboratories and offices are based in beautiful Vancouver, British Columbia.Role Summary: Genevant works closely with many pharma companies employing our LNP delivery platform to develop novel nucleic acid therapeutics. To support the high demand for our LNP technology, we have established an in-house manufacturing group to supply LNP formulated nucleic acids for numerous research programs. This brings an exciting opportunity for a highly motivated and skilled individual to join our organization as Manager, In-House Manufacturing. As Manager of In-House Manufacturing, you will lead a team of manufacturing associates to prepare, test and ship LNP drug products for multiple partner programs. This role reports to the Director of Manufacturing and Supply Chain. Selection for this role is based on proven competence and excellent performance. The work is fast-paced and demands close attention to detail.Responsibilities:

• Lead the in-house manufacturing team and manage the formulation of nucleic acid-LNP drug product batches for pre-clinical evaluation
• Coordinate the release testing, packaging and shipping of the LNP products
• Develop and maintain a master manufacturing schedule
• Work closely with process experts in the process development team to implement new manufacturing methods, in-process test methods and process equipment
• Prepare/approve technical documents including analytical test reports, master production records, SOPs, development reports, manufacturing instructions, and investigation reports
• Contribute to supply chain management via timely ordering of raw materials and consumables. Monitor inventories, communicate with vendors and prepare purchase orders to ensure timely re-stocking of long lead-time, custom manufactured items so manufacturing is never interrupted
• Maintain the manufacturing suite in a clean and highly organized state. Monitor equipment performance and schedule maintenance as needed.
• Conduct the training, supervision and performance evaluation of the CFT staff. Ensure their needs are addressed either directly or through support from within the organization. Assist the team to work at their best possible level and ensure they have access to training resources to improve their abilities
• Coordinate with and report to Project Management regarding the quality and delivery schedule of product batches
• Ensure the CFT group maintains strong intra-company communications regarding product requirements and production methods
• Provide weekly reports to your supervisor and to the Genevant CMC management team regarding the output and performance of the CFT

Qualifications:

• BSc or MSc in Chemistry, Biochemistry, Chemical Engineering or a related discipline, as relevant to the pharmaceutical/biotechnology industry
• A proven record of achievement and at least 4 years experience with laboratory production
• A thorough understanding of laboratory hygiene practices required to sanitize process equipment and minimize microbial contamination while processing
• Knowledge of nucleic acid-based therapeutics, lipid delivery systems is preferred
• Proven ability to work effectively in a team environment within a diverse organization
• A strong capability for independent planning and completion of production activities
• At least 2 years supervisory experience
• Enthusiasm and aptitude for hands-on data analysis and laboratory bench work
• Highly effective multi-tasking skills
• Strong written and oral communications skills
• Proficiency with the Microsoft Office suite

gcBO8OL3hWJob Type: Full-timeQuick Apply

• Terms & Conditions
• New Privacy
• Privacy Center
• Accessibility

For Job Seekers

• Browse Jobs
• Advanced Job Search
• Emplois Quebec

For Employers

• Post a Job

Stay Connected