Research Technician - Jobs in Vancouver, BC

Job Description

Staff - Non UnionJob CategoryNon Union Technicians and Research AssistantsJob ProfileNon Union Salaried - Research Assistant /Technician 4Job TitleResearch TechnicianDepartmentResearch | Leslie | Michael Smith Laboratories | Faculty of ScienceCompensation Range$4,558.75 - $5,354.67 CAD MonthlyPosting End DateFebruary 13, 2023Note: Applications will be accepted until 11:59 PM on the day prior to the Posting End Date above.Job End DateFeb 28, 2024At UBC, we believe that attracting and sustaining a diverse workforce is key to the successful pursuit of excellence in research, innovation, and learning for all faculty, staff and students, and is essential to fostering an outstanding work environment. Our commitment to employment equity helps achieve inclusion and fairness, brings rich diversity to UBC as a workplace, and creates the necessary conditions for a rewarding career.Job SummaryThis position will use biophysical techniques to research the therapeutic mechanisms of genetic medicines, and their interactions with mRNA targets. The work will focus on applying Convex Lens-induced Confinement (CLiC) single-molecule imaging technology, fluorescence lifetime correlation spectroscopy (FLCS), and bulk fluorescence assays to quantify the interactions between these biomolecules and develop a better understanding of their therapeutic mechanisms. Further, nanofabrication techniques will be used to make glass substrates with embedded nanowells for CLiC microscopy. Techniques employed will include new biophysical and measurement capabilities, as well as biotechnology, wet lab, molecular biology, clean room, and nanofabrication techniques.Organizational StatusReports to the Principal Investigator. Communicates regularly with an interdisciplinary team of scientists and engineers, and industry partners including ScopeSys Inc.Work Performed

• Conducts diverse lab work such as DNA/RNA/protein preparation, running bulk fluorescence assays using a microplate reader, and specialized microscopy experiments using single-molecule CLiC methodology.
• Designs and performs experiments. This could include the structural analysis of DNA/RNA oligomers; fluorescence labeling; biophysical assays; nanofabrication and lithography; enzyme interactions with oligonucleotides; and surface chemistry and passivation treatments.
• Develops novel techniques and methodologies to achieve research goals.
• Analyzes experiment results and troubleshoots problems as needed.
• Searches, reviews and determines the applicability of new technology and protocols related to work.
• Documents and communicates experimental plans and results in different formats and timescales, from weekly research meetings to contributing to scientific manuscripts.
• Fabricates arrays of nanowells on glass substrates for use in trapping single molecules in CLiC microscopy. This includes using micro/nanofabrication equipment in a clean room.
• Maintains a clean and orderly working environment in the lab.
• Assists the lab manager in performing tasks such as lab organization, purchasing supplies and procurement of small equipment.
• Carries out any other related duties as required in keeping with the qualifications and requirements of positions in this classification.

Consequence of Error/JudgementAttention to detail and exercising judgement is required. The Technician will be responsible for reporting errors or problems in their work in a timely manner and participate in a resolution to correct those errors. Improperly conducted procedures may warrant the repetition of experiments affecting the timeline of the research project and wasting of resources.Supervision ReceivedReports to the Principal Investigator. Works under minimum supervision, receiving specific instructions only on unusual problems or on matters which depart significantly from established policy and procedure. Meets regularly with the project team to discuss progress and direction.Supervision GivenThe Technician will work as part of a team. May have joint responsibility for supervising and training more junior personnel.Minimum QualificationsCompletion of a university degree in a relevant discipline or technical program and a minimum four years of related experience or an equivalent combination of education and experience. Some positions may require a graduate degree.Preferred QualificationsBachelor’s degree in the field of biophysics, bioengineering, biomedical engineering, physics, chemistry or biochemistry. Demonstrated experience in biophysics, surface science and chemistry, data analysis, coding, molecular biology, and microscopy. Computer experience with MS Word, Excel, PowerPoint, and MATLAB. Experience with micro/nanofabrication techniques such as photolithography, thin film deposition, and reactive ion etching in a clean room environment is a plus.Skills

• Ability to maintain accuracy and attention to detail.
• Ability to identify problems and contribute to solutions.
• Effective oral and written communication skills.
• Effective interpersonal, multi-tasking, time-management, and organizational skills.
• Demonstrate initiative in collaborating on setting priorities and meeting deadlines.
• Demonstrate flexibility and responsiveness to changing needs.
• Self-motivated and take initiative to perform work when supervisors are not present.
• Ability to work effectively independently and in a team environment.

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