Pre-Clinical Imaging Scientist/Research Associate - Jobs in Chalk River, ON

Job Description

INTROCNL R&D Health mission is to advance knowledge in radiobiology and provide a unique range of isotopes and pre-clinical services to maintain and improve the health of all Canadians.CNL is establishing an in vivo rodent imaging laboratory to advance the safety and performance of radiopharmaceuticals in cancer treatment, and elucidate their mechanisms of action.The Biology R&D Facility is currently operating an optical/CT imaging system and has recently commissioned a high performance small animal preclinical PET/SPECT/CT Imaging system and. CNL is looking for a strong scientist who will be instrumental in developing and growing the molecular imaging laboratory that will perform research in optimising therapeutic options and support the preclinical evaluation of radiopharmaceuticals for imaging and/or therapy of cancer. The successful candidate will work in collaboration with interdisciplinary preclinical project teams to develop and implement advanced imaging techniques for radiopharmaceutical therapy evaluation and performance enhancement. They will be responsible for designing and enhancing rodent imaging and therapeutic studies, serving as a Subject Matter Expert, analysing preclinical data and disseminating results to project teams, stakeholders, customers, and federal and academic partners. CNL is seeking a highly motivated candidate with demonstrated experience in molecular imaging and the ability to work as part of a collaborative research.DUTIESThe incumbents overall responsibilities will include, but are not limited to, the following:

• Evaluate and develop imaging and therapeutic strategies for novel isotopes (including alpha emitters) and radio immune-conjugates /probes/biomarkers in animal tissues and cells.
• Apply practical and theoretical knowledge and provide guidance for preclinical imaging equipment, instrumentation and software analysis for a variety of imaging modalities, which may include CT, PET, SPECT, Cerenkov, and Optical systems.
• Act as technical subject matter expert for relationships with academic researchers, imaging-related vendors, commercial customers and stakeholders.
• Manage and configure imaging-related software packages and software licenses, data acquisition, image repositories and data pipelines in consultation with CNL IT department end users and vendors.
• Manage all aspects of in vivo rodent Imaging Facility to support drug discovery, preclinical research and basic research, including research protocols, radiation safety/shielding, dosimetry.
• Consult on radio-labelling of vectors and conjugates and dose calibrations for radio–isotope administrations for in rodents for in vivo imaging or therapeutic studies.
• Responsibility for imaging equipment maintenance, repair and upgrades.
• Ensure Facility regulatory compliance and application of ALARA Principles.
• Oversee required changes to the Radioisotope Laboratory and/or Radiological Zoning documentation, as required.
• Develop, modify, and update Standard Operating Procedures (SOPs).

Mentor and train staff on equipment and software operational, analytical and calibration processes.QUALIFICATIONS

• Doctoral degree in medical physics, applied mathematics, biomedical engineering, or related fields, with up to five years’ experience post-graduation. Experience in molecular imaging is essential, and preclinical PET/SPECT/CT imaging is preferred. Alternatively, a M.Sc. degree with 3-8 years of relevant experience in Preclinical Molecular Imaging in an industrial or academic setting is required.
• An advanced understanding of theoretical and practical aspects of equipment and software applications used for preclinical imaging using PET, SPECT, CT, Optical or other relevant imaging modalities.
• Operational Experience coordinating, conducting and analysing preclinical imaging studies and previous experience working at an in vivo imaging platform with multi-modality imaging expertise is desirable.
• Experience with imaging data analysis with common imaging applications and software and experience with programming languages is highly desirable.
• Demonstrated independence in experimental design, data analysis and interpretation and track record of successful internal and external scientific collaborations.
• Prior experience working with radiopharmaceutical agents, both imaging and therapeutic.
• Ability to independently assess and make recommendations concerning the maintenance and upgrade of preclinical imaging equipment and software.
• Knowledge of radiation protection is desired, and Group-2 Radiation Protection training is required (provided by CNL).
• Ability to independently perform data analysis and deliver written and oral summaries of work.
• Excellent written and verbal communication skills including presentation skills.
• Ability to interact professionally and confidently with collaborators, customers and users, and to provide training to CNL internal staff.
• Excellent problem identification and problem-solving skills with the ability to work effectively in a collaborative environment.
• Operational Experience coordinating, conducting and analysing preclinical imaging studies and previous experience working in a rodent in vivo imaging facility with cross-imaging modality expertise is desirable.
• Experience with imaging data analysis with common imaging applications and software and experience with programming languages is preferred.

CNL is committed to providing an atmosphere free from barriers that promote equity, diversity and inclusion in achieving our mission. CNL welcomes and celebrates employees, stakeholders and partners of all racial, cultural, and ethnic identities.CNL also supports a workplace environment and a corporate culture built on our Core Values: Respect, Teamwork, Accountability, Safety, Integrity and Excellence, which encourage equitable employment practices and career prospects inclusive of accommodations for all employees.CNL is committed to being an equal-opportunity employer. If you require accommodation measures during any phase of the hiring process, please inform the Talent Acquisition Specialist with whom you are in contact. All information received in relation to accommodation requests will be kept confidential.The Chalk River Laboratories site is located on the unceded and unsurrendered territory of the Algonquin Anishinaabe people. As an organization, CNL recognizes and appreciates their historic connection to this place. CNL also recognizes the contributions that First Nations, Métis, Inuit and other Indigenous Peoples have made, both in shaping and strengthening this community in particular, and this province and country as a whole.Quick Apply

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